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While both Cosentyx (secukinumab) and nonsteroidal anti-inflammatory drugs (NSAIDs) have been found to reduce disease progression in people with ankylosing spondylitis, analysis of trial data shows that the anti-rheumatic therapy worked slightly better over a two-year period. However, while Cosentyx did a somewhat better job in…

Inhibiting both IL-17A and IL-17F signaling molecules with the investigational antibody bimekizumab can effectively improve the outcomes of patients with ankylosing spondylitis, according to clinical results. The study, “Dual Neutralisation of Il-17A and Il-17F with Bimekizumab Was Associated with Improvements…

Europe’s umbrella organization for 800 rare disease associations has developed a sweeping initiative to help the continent’s 30 million rare disease patients and their caregivers learn about their conditions, find assistance and receive treatment. Eurordis-Rare Diseases Europe hopes to improve the current piecemeal treatment and support program with a holistic,…

People with rare diseases know that the right government policies can make a big difference in the quality of their own lives, and those of their caregivers. But most lawmakers aren’t experts in even one well-known disease — let alone the world’s estimated 7,000 rare disorders. So how does the…

People with axial spondyloarthropathy are more prone to develop additional disorders — called “multimorbidity” — which is associated with worse disease outcomes, according to a recent Irish study. The study, “Multimorbidity is Common in Axial Spondyloarthropathy and is Associated with Worse Disease Outcomes: Results from the ASRI cohort,”…

Both the lifetime risk of valvular heart disease (VHD) and the need for pacemakers markedly increase with age for people with ankylosing spondylitis (AS). But these risk rates are only slightly higher than those for people without the disease, a U.S. population-based study shows. In light of these…

Problems in spinal mobility are common in people living with ankylosing spondylitis (AS) for more than 10 years, a Swedish study shows. The most prevalent problem is difficulty in bending the spine sideways, which associates with worse mobility problems later on. The study, “Long‐term spinal mobility in ankylosing…

People with ankylosing spondylitis and psoriatic arthritis both are prone to developing additional diseases (comorbidities). However, only in patients with psoriatic arthritis do comorbidities seem to have a negative impact on physical function, according to a study. The study, “Impact of Comorbidity on Physical Function in Patients with Ankylosing…

People with non-radiographic axial spondyloarthritis share the same disease comorbidities as those affected by ankylosing spondylitis, which may hold implications regarding treatment management, a study finds. The findings, “Comparison of comorbidities and treatment between ankylosing spondylitis and non-radiographic axial spondyloarthritis in the United States,” were published in Rheumatology.

RaDaR, the catchy new name for the U.S. government-run Rare Diseases Registry Program, aims to help patient advocacy groups with limited resources build their own disease registries. The site was developed by the National Center for Advancing Translational Sciences (NCATS), a division of the National Institutes of…