People with ankylosing spondylitis (AS) face difficulties in diagnosis and treatment, must deal with the debilitating effects of disease symptoms, and handle adjustments in social roles, often while contending with a lack of understanding and support — all factors that add to an increased disease burden for patients. That’s…
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Certain microRNAs, molecules involved in controlling gene activity, were dysregulated in adults with axial spondyloarthritis (axSpA), a study found. Altered levels of these microRNAs were linked with elevated blood levels of pro-inflammatory signaling proteins implicated in the development and activity of axSpA. MicroRNAs as biomarkers “could help improve the early…
Ankylosing spondylitis (AS) is a type of arthritis that mainly affects the joints of the spine. Inflammation of the spaces between the vertebrae causes back pain and stiffness.
There is no single specific test to diagnose AS, and many of the symptoms (such as back pain) also can be caused by other conditions. A diagnosis often involves checking for common hallmarks of AS.
Patients’ symptoms usually progress gradually over time. They may be erratic because the type and severity of the symptoms can improve, worsen, or completely stop for periods of time.
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