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Women maintain Cimzia blood levels throughout pregnancy

Women with axial spondyloarthritis (axSpA) or other inflammatory diseases maintained stable therapeutic levels of Cimzia (certolizumab pegol) throughout pregnancy, as announced by UCB, the therapy’s developer. The results, from the open-label Phase 1b CHERISH clinical trial (NCT04163016), were presented at the European Congress of Rheumatology held…

Alvotech, collaborators prep for Humira biosimilar launch in US

Alvotech’s high-dose biosimilar of Humira (adalimumab) — a medication approved for ankylosing spondylitis (AS) and other inflammatory diseases — which was cleared by federal regulators earlier this year, will soon be launched in the U.S. under the brand name Simlandi. A biosimilar is a medication containing the…

Risk of progressing to AS within 10 years is low, study finds

While some people with recent-onset axial spondyloarthritis whose joint damage isn’t visible on an X-ray will progress within 10 years to ankylosing spondylitis (AS), where joint damage becomes evident on an X-ray, the risk is relatively low, a French study found. The risk was about halved in patients on TNF inhibitors, but more…