Mild hearing loss is common among people with ankylosing spondylitis, particularly in older patients regardless of disease severity, researchers have found. The study, “Hearing loss in ankylosing spondylitis,” was published in the International…
Inhibiting both IL-17A and IL-17F signaling molecules with the investigational antibody bimekizumab can effectively improve the outcomes of patients with ankylosing spondylitis, according to clinical results. The study, “Dual Neutralisation of Il-17A and Il-17F with Bimekizumab Was Associated with Improvements…
Progressing disease, older age, and lower education can significantly affect ankylosing spondylitis patients’ ability to cope with the challenges and burden associated with their illness, a study has found. Multidisciplinary clinical teams should take these findings into consideration to prevent additional health problems and provide the best care and support…
A high-fat diet and long-term exposure to air pollution are both associated with worse outcomes in patients with ankylosing spondylitis, a study shows. The study, “Effect of food intake and ambient air pollution exposure on ankylosing spondylitis disease activity,” was published in the journal Advances…
Treatment with anti-TNF-alpha therapies can lead to improved lumbar spine curvature and better clinical outcomes in patients with ankylosing spondylitis, study shows. The study, “Radiologic parameters of ankylosing spondylitis patients treated with anti-TNF-α versus nonsteroidal anti-inflammatory drugs and sulfasalazine,” was published in the European Spine Journal.
Determining blood levels of two proteins — osteoprotegerin (OPG) and receptor activator of nuclear factor-kB ligand (RANKL) — may help identify patients at risk of having ankylosing spondylitis, a review study suggests. However, these potential biomarkers should be used carefully as they could be influenced by race, inflammatory factors,…
Analyzing the circulating levels of a specific RNA molecule, known as MEG3, may be used as a reliable and effective biomarker for the diagnosis and prognosis of ankylosing spondylitis patients, a study has found. The study, “lncRNA MEG3 is downregulated in ankylosing spondylitis…
People with ankylosing spondylitis have diminished health-related quality of life (HRQoL) compared to the general population, a Swedish study shows. The study, “Factors related to health-related quality of life in ankylosing spondylitis, overall and stratified by sex,” was published in the journal Arthritis Research & Therapy.
Approximately 10 to 23 percent of people with ankylosing spondylitis have hip joint involvement that can be managed with tumor necrosis factor-α (TNF-alpha) blocking therapy, a study shows. The study, “High prevalence of hip involvement and decrease in inflammatory ultrasound lesions…
TrialSpark, a technology company that works to increase access and integrate trial participation into patients’ everyday lives, has teamed up with Novartis, a global healthcare company, to activate their first clinical trial sites. This patient-centered model for clinical trials will enable patients to enroll in studies from their doctor’s office, rather…
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