Treatment with Erelzi (etanercept) is well-tolerated by people with ankylosing spondylitis (AS) and other rheumatic diseases, including rheumatoid arthritis (RA) and progressive psoriatic arthritis, an early analysis of a real-world study suggests. The findings also indicated that Erelzi reduced disease activity in patients with RA, the only group…
Rare disease-themed videos glowed on a large screen before an audience of people in wheelchairs, with crutches, and bearing oxygen tanks this Nov. 9 and 10 in San Francisco. Disorder: The Rare Disease Film Festival strives to eventually host a film about every one of the nearly 7,000 rare…
Biogen has signed an agreement with Samsung Bioepis that includes an option of extending commercialization rights to three biosimilars of TNF inhibitor therapies used for ankylosing spondylitis (AS) — Benepali (etanercept), Flixabi (infliximab), and Imraldi (adalimumab) — for an additional five years in Europe. The…
Treatment with the experimental therapy bimekizumab is safe and shows sustained efficacy over 48 weeks in people with ankylosing spondylitis (AS), data from a Phase 2b trial show. In addition, the use of biologic therapies for AS is associated with more comorbidities and higher use of other treatments…
Continuous use of non-steroidal anti-inflammatory drugs (NSAIDs) increases the risk of hypertension by 12% in people with ankylosing spondylitis (AS), a prospective study suggests. The study, “Nonsteroidal Anti-inflammatory Drug use is Associated with Incident Hypertension in Ankylosing Spondylitis,” was published in the journal Arthritis Care &…
Women with ankylosing spondylitis (AS) stay with TNF inhibitor treatment for significantly shorter periods than men, mostly due to ineffectiveness, and they are at higher risk of developing infections while on these biological therapies, according to real-world data from the Netherlands. The study, “Gender differences in retention rate of…
Gout —a common, painful form of arthritis that causes swollen, red, hot, and stiff joints — may be more common in people with ankylosing spondylitis (AS) than in the general population, a study suggests. Among people with AS, this association is particularly likely in patients ages 40-60,…
The European Commission has approved a label update for Cosentyx (secukinumab) that will allow healthcare providers to prescribe doses of up to 300 mg — twice what was previously approved — for people with active ankylosing spondylitis (AS). Cosentyx, developed and marketed by Novartis, is a…
Men, people who are employed, have a lower income, perceive less control over their lives, and are less satisfied about their social roles, are among those with ankylosing spondylitis (AS) more prone to depression, a Dutch study has shown. While disease activity contributes only moderately to depression,…
Treatment with Xeljanz (tofacitinib citrate) led to a clinically meaningful reduction in spinal and sacroiliac joint inflammation in approximately one-third of ankylosing spondylitis (AS) patients taking part in a Phase 2 clinical trial. The study, “Tofacitinib is associated with attainment of the minimally important…
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