One year of UCB Biopharm‘s investigational therapy bimekizumab, administered subcutaneously (under the skin) once every four weeks, resulted in sustained improvement in the signs and symptoms of axial spondyloarthritis (axSpA), according to late-breaking data from two BE MOBILE Phase 3 clinical trials. axSpA is a type of inflammatory…
Early initiation of anti-tumor necrosis factor (TNF) medications may be associated with an increased risk of cardiovascular events in people with ankylosing spondylitis (AS), a study suggests. “We designed the study with the overall hypothesis that the use of TNF inhibitors, which reduce inflammation and thus cardiovascular risk,…
Engaging in online yoga classes, or tele-yoga, may help people with ankylosing spondylitis (AS) relieve pain, overcome some functional limitations, and improve their mental health, a study from India suggests. The study, “Tele-yoga in the management of ankylosing spondylitis amidst COVID pandemic: A prospective randomized controlled trial,” was…
Motto Health has launched an all-in-one virtual health platform to expand access to comprehensive rheumatology care for people with chronic autoimmune conditions, including ankylosing spondylitis . The new app offers virtual rheumatology clinic visits, personalized lifestyle coaching, and symptom tracking, all with the goal of closing the existing…
The diagnosis of rare diseases such as akylosing spondylitis (AS) is complex and often delayed. A partnership between U.S. researchers aims to use artificial intelligence to develop a software to diagnose rare diseases sooner. The four-year project, led by researchers at the University of Florida Health and the Perelman School…
People with ankylosing spondylitis (AS) who experience uveitis, an inflammatory condition of the eye, have a significantly higher risk of stroke than those without this AS symptom, according to a large medical database analysis. Uveitis in AS also was linked with an increased incidence of known stroke…
People with ankylosis spondylitis (AS) may not be at an increased risk of developing severe symptoms of COVID-19, according to a large U.S. study. That’s not the case, however, with those with rheumatoid arthritis, another immune-mediated disease, who were found to have a 20% higher risk of developing severe…
An analysis of genetic sequencing data has identified potential new biomarkers for diagnosing ankylosing spondylitis (AS). Specifically, scientists analyzed mRNAs, or the templates used to generate a protein from DNA, and found that the levels of three — Cxcr6, IL17RA, and Lrrfip1 — were associated with disease severity and…
Researchers have described a successful bone surgery to correct a rare type of spinal deformity in a man with ankylosing spondylitis (AS) that had prevented him from facing forward while walking — marking the first case report of this type of spinal surgery for an AS patient. While AS…
Almost all people with axial spondyloarthritis (axSpA) who had worsening disease severity after stopping Taltz (ixekizumab) saw improvements after restarting the therapy, according to data from a Phase 3 withdrawal study. The majority (71%) reached a state of disease remission after restarting treatment. These findings provide important information about…
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