The diagnosis of rare diseases such as akylosing spondylitis (AS) is complex and often delayed. A partnership between U.S. researchers aims to use artificial intelligence to develop a software to diagnose rare diseases sooner. The four-year project, led by researchers at the University of Florida Health and the Perelman School…
People with ankylosing spondylitis (AS) who experience uveitis, an inflammatory condition of the eye, have a significantly higher risk of stroke than those without this AS symptom, according to a large medical database analysis. Uveitis in AS also was linked with an increased incidence of known stroke…
People with ankylosis spondylitis (AS) may not be at an increased risk of developing severe symptoms of COVID-19, according to a large U.S. study. That’s not the case, however, with those with rheumatoid arthritis, another immune-mediated disease, who were found to have a 20% higher risk of developing severe…
An analysis of genetic sequencing data has identified potential new biomarkers for diagnosing ankylosing spondylitis (AS). Specifically, scientists analyzed mRNAs, or the templates used to generate a protein from DNA, and found that the levels of three — Cxcr6, IL17RA, and Lrrfip1 — were associated with disease severity and…
Researchers have described a successful bone surgery to correct a rare type of spinal deformity in a man with ankylosing spondylitis (AS) that had prevented him from facing forward while walking — marking the first case report of this type of spinal surgery for an AS patient. While AS…
Almost all people with axial spondyloarthritis (axSpA) who had worsening disease severity after stopping Taltz (ixekizumab) saw improvements after restarting the therapy, according to data from a Phase 3 withdrawal study. The majority (71%) reached a state of disease remission after restarting treatment. These findings provide important information about…
An eight-week Pilates group training program for people with ankylosing spondylitis (AS) lowered disease activity, improved spine flexibility, and led to gains in endurance, balance, and quality of life, a recent study showed. Several of these benefits were not seen among those who did an individual at-home exercise program,…
Sudo Biosciences has secured $37 million in series A financing to back the development of TYK2 inhibitors as potential anti-inflammatory medicines for immune-mediated inflammatory conditions, such as ankylosing spondylitis (AS). The goal, the company said in a press release announcing the new funding, is to move the…
Diarrhea, cold-like symptoms, itchy skin, and rash are the most common real-world side effects associated with Cosentyx, an approved treatment for ankylosing spondylitis (AS), a study has found. Such side effects typically emerge in the first month of using the medication, according to the analysis, which included information…
Long-term treatment with under-the-skin injections of brodalumab safely and effectively reduced disease activity in people with axial spondyloarthritis (axSpA), according to final data from a Phase 3 trial. axSpA is a type of chronic inflammatory arthritis affecting the joints of the spine, chest, and pelvis. Ankylosing spondylitis (AS) is…
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