Organizers of this year’s World AS Day, seek to raise awareness about the signs and symptoms of axial spondyloarthritis (axSpA), a disorder that’s thought to affect more than 50 million people globally. The day will be observed on Saturday, May 4. The campaign is coordinated by the…

Changes in the abundance of a bacteria called Escherichia_Shigella within the digestive tract of people with inflammatory bowel disease (IBD) may be related to the development of axial spondyloarthritis (axSpA), a new study revealed. Among the IBD patients, 1 out of every 5 had an axSpA diagnosis, and half lived…

Adults with axial spondyloarthritis (axSpA) remained on golimumab longer than any other TNF inhibitor, according to a real-world analysis of medical records. Although adalimumab (marketed as Humira and biosimilars) was the most commonly prescribed first- and second-line TNF inhibitor, patients stayed with golimumab (marketed…

Uveitis, a form of eye inflammation, and lower socioeconomic status are both linked to a longer time to diagnosis in people with axial spondyloarthritis, known as axSpA, a study reports. In contrast, older age at symptom onset is associated with shorter delays, the researchers noted. “These results suggest that…

A year of treatment with bimekizumab was safe and significantly eased symptoms of axial spondyloarthritis (axSpA) in participants from two Phase 3 clinical trials, data show. “Results at [one year] from the BE MOBILE trials suggest that [bimekizumab] is an effective treatment option resulting in sustained efficacy across…

Anxiety and depression, but not resilience, were found to be linked to poorer overall health and functioning in people with axial spondyloarthritis (axSpA) — mostly men and almost all Chinese — who took part in a study done by researchers in Singapore. “Clinicians could consider routinely screening for anxiety and…

The first patient has been randomized in a pivotal Phase 3 program testing oral filgotinib in adults with active axial spondyloarthritis (AxS), including ankylosing spondylitis (AS). The OLINGUITO program (NCT05785611) consists of two placebo-controlled, parallel clinical trials into the safety and efficacy of filgotinib in adults with…

Pregnant women with axial spondyloarthritis (AxS) are not at an increased risk of preeclampsia, unlike those with other rheumatic conditions, a new study suggests. Using more than 3,000 health records, researchers in Sweden and Denmark evaluated preeclampsia risk in pregnant women with rheumatoid arthritis (RA), AxS, and psoriatic arthritis. “Based…

Almost all people with axial spondyloarthritis (axSpA) who had worsening disease severity after stopping Taltz (ixekizumab) saw improvements after restarting the therapy, according to data from a Phase 3 withdrawal study. The majority (71%) reached a state of disease remission after restarting treatment. These findings provide important information about…

Women with axial spondyloarthritis (axSpA) are diagnosed significantly later compared to men, according to a new study. The presence of widespread pain and arthritis were the early symptoms most commonly found in women and linked with a diagnosis delay. The study, “Gender-related differences in axial spondyloarthritis (axSpA)…