Author Archives: Lindsey Shapiro

Older AS patients may be at greater risk for some blood cancers

Ankylosing spondylitis (AS) patients 65 and older may be at an increased risk of certain blood cancers compared with older adults in the general population, according to a recent study. The risk for these cancers, however, was similar among AS patients and people with another inflammatory condition called inflammatory…

Plans Afoot to Create Algorithm That Predicts Treatment Responses

The biotech company Girihlet will collaborate with Mayo Clinic to develop an algorithm that evaluates the effects of immune-suppressing treatments in patients with ankylosing spondylitis (AS), Girihlet announced. Under the so-called “know-how agreement,” Girihlet will use its proprietary ImmuneScanner technology to monitor changes in immune T-cells…

Evidence for Most AS Blood Biomarkers Weak: Umbrella Review

Platelet counts and blood levels of inflammatory proteins interleukin-23 (IL-23) and interleukin-17 (IL-17) were identified as the strongest potential non-genetic biomarkers of ankylosing spondylitis (AS) in a recent umbrella review study. The study, which looked at 43 previously identified biomarkers, found the evidence was weak for most others. The…

Water Exercises Lead to Significant Gains for Men With AS in Study

Six weeks of water-based exercises — consisting of stretching or Pilates — led to significant reductions in pain and improvements in spine flexibility, functional capacity, and quality of life for men with ankylosing spondylitis (AS), according to a recent study in Iran. While both types of exercise led to…

Motto Launches Virtual Care App for Autoimmune Diseases

Motto Health has launched an all-in-one virtual health platform to expand access to comprehensive rheumatology care for people with chronic autoimmune conditions, including ankylosing spondylitis . The new app offers virtual rheumatology clinic visits, personalized lifestyle coaching, and symptom tracking, all with the goal of closing the existing…

Genetic Analysis Identifies Potential Biomarkers to Help Diagnose AS

An analysis of genetic sequencing data has identified potential new biomarkers for diagnosing ankylosing spondylitis (AS). Specifically, scientists analyzed mRNAs, or the templates used to generate a protein from DNA, and found that the levels of three — Cxcr6, IL17RA, and Lrrfip1 — were associated with disease severity and…

Group Pilates Superior to At-home Exercise for Patients in Study

An eight-week Pilates group training program for people with ankylosing spondylitis (AS) lowered disease activity, improved spine flexibility, and led to gains in endurance, balance, and quality of life, a recent study showed. Several of these benefits were not seen among those who did an individual at-home exercise program,…

Real-world Study Reveals Side Effects Linked to Cosentyx

Diarrhea, cold-like symptoms, itchy skin, and rash are the most common real-world side effects associated with Cosentyx, an approved treatment for ankylosing spondylitis (AS), a study has found. Such side effects typically emerge in the first month of using the medication, according to the analysis, which included information…

Long-term Brodalumab Treatment for axSpA Supported by Phase 3 Data

Long-term treatment with under-the-skin injections of brodalumab safely and effectively reduced disease activity in people with axial spondyloarthritis (axSpA), according to final data from a Phase 3 trial. axSpA is a type of chronic inflammatory arthritis affecting the joints of the spine, chest, and pelvis. Ankylosing spondylitis (AS) is…