Author Archives: Joana Carvalho

People with axial spondyloarthritis (axSpA) who had higher pain sensitivity were more likely to have worse clinical outcomes, according to a study that found chronic pain to be common in these patients. The study, “Chronic pain and assessment of pain sensitivity in patients with axial spondyloarthritis: Results…

Gilead Sciences has suspended enrollment in two Phase 3 trials studying the effects of filgotinib, an anti-inflammatory therapy currently being investigated in several inflammatory conditions, in patients with ankylosing spondylitis (AS). The trials, SEALION2-NAÏVE (NCT04483700) and SEALION1-IR (NCT04483687), set out to determine if filgotinib is potentially…

Non-radiographic axial spondyloarthritis (nr-axSpA) has been given a diagnostic code, M46.80, that will be used to identify the condition in the 10th edition of the International Classification of Diseases, Clinical Modification (ICD-10-CM), a repository that contains the official codes of all types of diseases. The updated ICD-10-CM document containing…

Low levels of Humira (adalimumab) early in the course of treatment and the presence of neutralizing autoantibodies in the blood of people with ankylosing spondylitis (AS) are associated with failure to respond to this treatment, a study says. The study, “Early adalimumab and anti-adalimumab antibody…

Treatment with Cosentyx (secukinumab) continues to be safe and to ease symptoms in people with active ankylosing spondylitis (AS) through three years of use, new data from a Phase 3 trial show. The three-year data were reported in a study, titled “Secukinumab 150/300…

Treatment with Simponi Aria (golimumab) led to clinically meaningful improvements in health-related quality of life in adults with ankylosing spondylitis after four months — benefits that were maintained over one year, a Phase 3 trial shows. The findings were presented in a poster, titled “Effects of…

Treatment with Erelzi (etanercept) is well-tolerated by people with ankylosing spondylitis (AS) and other rheumatic diseases, including rheumatoid arthritis (RA) and progressive psoriatic arthritis, an early analysis of a real-world study suggests. The findings also indicated that Erelzi reduced disease activity in patients with RA, the only group…

Gout —a common, painful form of arthritis that causes swollen, red, hot, and stiff joints — may be more common in people with ankylosing spondylitis (AS) than in the general population, a study suggests. Among people with AS, this association is particularly likely in patients ages 40-60,…

A specific type of MRI called diffusion-weighted imaging is sensitive enough to identify patients with early signs of axial spondyloarthritis, a study has f0und. Results of the study, “Diffusion-weighted Imaging Is a Sensitive and Specific Magnetic Resonance Sequence in the Diagnosis of Ankylosing Spondylitis,” were published in…

A physical intervention program based on pilates training may be beneficial for people with ankylosing spondylitis, a study finds. The research, “One Year of Pilates Training for Ankylosing Spondylitis: A Pilot Study,” was published in The Journal of Alternative and Complementary Medicine. Ankylosing spondylitis (AS) is…