Axial spondyloarthritis patients who do not respond initially to treatment with TNF-alpha inhibitors (TNFi) share some commonalities, researchers discovered in a study aimed at evaluating factors associated with TNFi failure. In particular, researchers found these patients tend to be older, lack a protein marker associated with the disease, have…
Patients with axial spondyloarthritis (axSpA) who quit smoking have lower disease activity, better physical function, and a better quality of life than those who smoke, a study reports. Researchers call for targeted interventions to promote smoking cessation in patients with axSpA. AxSpA is a group of disorders that includes ankylosing…
A study of patients with ankylosing spondylitis, rheumatoid arthritis, and psoriatic arthritis who switched from Remicade (infliximab) therapy to a biosimilar, sold as Remsima or Inflectra (CT-P13), showed that 24% of patients stopped taking the therapy within six months for reasons that appear unrelated to the therapy’s health benefits. The…
Patients with chronic inflammatory disorders, including ankylosing spondylitis, are at a higher risk of experiencing multiple cardiometabolic events than matching controls with no inflammatory disease. The risk was almost three times higher for those treated with non-steroidal anti-inflammatory drugs (NSAIDs) compared with those without an inflammatory disease, leading researchers to urge…
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